CD274 and neoplasm: The expression of some of the HDACs not only shows a correlation with infiltrating lymphocytes, but has also been shown to associate with immune checkpoint expression, suggesting a possible role for these HDACs in the immune evasion of tumor cells: high levels of HDACs 1, 3, 6 and 8 were positively correlated with expression of the B7 homolog 1 checkpoint inhibitor (B7-H1) in gastric cancer.