Monosomy 3/loss of BAP1 expression is related to an inflammatory phenotype, which is characterized by the presence of tumor-infiltrating lymphocytes (TILs), tumor-associated macrophages (TAMs) and high expression levels of the Major Histocompatibility complex (MHC) proteins HLA Class I and HLA Class II [12,13,14,15,16]. Here, BAP1 is linked to neoplasm.