STING1 and neoplasm: Adjuvants bind onto pattern recognition receptors (PRRs), including toll-like receptors (TLRs), stimulator of IFN genes (STING) and NOD-like receptors (NLRs), which are present on epithelial (cancer) cells and innate immune cells, including DCs, and initiate immune responses against pathogens or tumor cells in secondary lymphoid organs [119].