We further examined and compared the dynamics and polarity of microglia/macrophages (Mφ) including resident Mφ (TMEM119 + Iba1+), M2-like Mφ (CD163 + Iba1+), and M1-like Mφ (iNOS + Iba1+) in the TME of the tumor control and dLGG–10, Lipo-DOX–2 and dLGG–10 + Lipo-DOX–2 group mice. Here, TMEM119 is linked to neoplasm.