HAVCR2 and cancer: However, the expression of other T-cell inhibitory receptors, such as Tim-3 (Havcr2) or Lag-3 [41,44], and the cancer immune evasion-related factor Pak4 [45] remained unchanged in MUP-uPA mice, regardless of the type of diet fed (Figure 5K) in parallel to the unchanged expression of indoleamine 2,3-dioxygenase (Ido1) [46].