HPV integration is most frequently detected in genic regions, most often cancer-related genes, such as oncogenes (e.g., TP63, MYC, ERBB2) or tumor suppressor genes (e.g., BCL2, FANCC, HDAC2, RAD51B, CSMD1) and to a lesser extent in miRNA regions [21,23]. The gene discussed is HDAC2; the disease is cancer.