The lncRNA assay yielded an AUC of 0.814, which was superior to those of the PSA (p < 0.001), f/tPSA (p < 0.001) and the base model (p = 0.065) for distinguishing PCa from patients with a negative biopsy (Figure 3d and Table 3). Here, KLK3 is linked to posterior cortical atrophy.