MF, co-existing diabetes mellitus, hyperlipidemia, leukocytes > 8.4 G/L, neutrophils > 5.48 G/L, monocytes > 0.55 G/L, LDH > 267.5 U/L, CRP levels > 1.4 mg/L, and treatment with RUX and anagrelide/IMIDs/interferon showed significant ORs when contrasting eGFR3 to eGFR2 or eGFR1. This evidence concerns the gene CRP and diabetes mellitus.