The promising results seen with HDACi in OAC in vitro studies have been further supported by Feingold et al. (2018) who evaluated the role of Thioredoxin Interacting Protein (TXNIP), a hypothesised tumour suppressor in OAC, that has previously been shown to be regulated by histone acetylation [36,65]. The gene discussed is TXNIP; the disease is neoplasm.