IL15 and cancer: The mice immunized with 3 × 105 IL-15:IL-15Rα-B16F10-OVA or IL-15:IL-15Rα-CT26-OVA per mouse, a dose which secreted IL-15:IL-15Rα at 70~160 pg/mL after 48 h, showed significantly delayed cancer cell growth compared with the groups immunized with no virus-infected or control BV-infected cancer cell groups (Figure S3D,F).