PINK1 and neuroblastoma: To determine which pathway is triggered by hypoxia, mitochondria were treated with the protonophore carbonyl cyanide m-chlorophenylhydrazone (CCCP), which dissipates the mitochondrial membrane potential, or TTFA, and the level of PINK1 was assessed in Tet21N and SK-N-BE(2) neuroblastoma cell lines using gel electrophoresis and subsequent Western blotting.