AR and neoplasm: However, compared to normal prostate, the aberrant AR form, including those of an AR splice variant (AR-V) with a molecular weight of ~80 kD and those with a molecular weight ~220 and ~250 kD (AR-HMW220 and AR-HMW250, respectively), were prominently expressed and elevated in tumor samples (Figure 2B, and Supplementary Figure S2A).