Furthermore, LNCaP/AR-shp53/shRB PCa cells were more resistant to CPT1 inhibitor (etomoxir) than LNCaP/AR cells as shown by the IC50 values of 83.36 μM vs. 12.48 μM and cell proliferation at different doses of etomoxir (37.5 and 75 μM, Figure 2D,E). The gene discussed is CPT1A; the disease is posterior cortical atrophy.