In the univariable analysis for good PSA response, initial presentation with both abnormal PSA and DRE (OR: 2.48, range, 1.11–5.58, p = 0.028), hypertension (OR: 2.1, range: 1.06–4.18, p = 0.033), and LDH value (OR: 0.2, range, 0.04–0.94, p = 0.041) were statistically significant factors. Here, KLK3 is linked to hypertensive disorder.