Interestingly, we also found the co-upregulation of GSE1, ANGPT2, VEGFA, KLK3 (kallikrein-3, prostate-specific antigen), CTNNB1, and TACSTD2 in localized PCa in the presence of the TMPRSS2-ERG fusion gene (Figure 2G). The gene discussed is KLK3; the disease is posterior cortical atrophy.