GSE1 and breast cancer: Recently, it was reported that the relatively unknown genetic suppressor element 1 (GSE1, KIAA0182), a proline-rich protein with coiled-coil domains, was overexpressed in patients with breast cancer and associated with poor prognosis; targeting GSE1 elicited the upregulation of miR-489-5p, with the repression of breast cancer cell proliferation, migration, and invasion [8].