An additional 15 novel breast cancer risk loci were identified in this study including PEX14, 2q24.1, 2q31.1, ADAM29, EBF1, TCF7L2, 11q13.1, 11q24.3, 12p13.1, PTHLH, NTN4, 12q24, BRCA2, RAD51L1-rs2588809, and MKL1. Of these, PTHLH reached genome-wide significance [79]. The gene discussed is BRCA2; the disease is breast cancer.