IQGAP1 and familial pancreatic carcinoma: Our analyses of RNA-seq data provided by The Cancer Genome Atlas (TCGA) demonstrated that higher levels of IQGAP1 transcripts are significantly correlated with poorer 5-year survival rates in patients with head and neck cancer [51], as well as those with pancreatic cancer (Figure 1), urothelial cancer (Figure 1), and poorer 3-year survival rates in melanoma patients (Figure 1).