In detail, employing the terminology that we described with this approach (see Methods), factor 1 (about 20% of total variance) links to the metabolic domain for the positive correlations with insulin and HOMA, visceral and subcutaneous fat, and TMI, WHtR, and BMI z-score; factor 2 (about 16% of total variance) relates to the amplitude and pulse domains, because it correlates positively with the alpha index, RR, RR variance, LF absolute and HF absolute, and negatively to HR. The gene discussed is INS; the disease is hydrops fetalis.