The average tumor weight in mice bearing Ace-1-Dkk-1YFP-LUC tumors (mean = 2.16 gms ± 0.32) was significantly greater compared with tumors with Ace-1-Vector YFP-LUC (mean = 0.44 gms ± 0.08) (Figure 6). This evidence concerns the gene ACE and neoplasm.