To combine the functional models with our Caco-2 cell model on subcellular PIP2 distribution, we selected a Caco-2 clone, which was stably transfected with the GPF-PLC-PH vector, showing appropriate GFP signals, and which formed confluent monolayers on PCF filter supports for TER measurements and could serve as infection model. This evidence concerns the gene HSPG2 and infection.