Of the 300 patients included in the study, DKA remained a rare presentation (0.3%).9 The incidence of thyroid disorders (hypothyroidism, thyrotoxicosis, painless thyroiditis, or thyroid storm) is estimated to be approximately 10% in patients treated with a single agent anti-PD-1/PD-L1.10 The gene discussed is PDCD1; the disease is thyroid gland disorder.