TLR7 and COVID-19: The studyidentified two different rare novel TLR7 loss-of-functionvariants (van der Made et al., 2020).The analysis of men with severe COVID-19 aged less than 60 years foundTLR7 deleterious missense variants in 2.1% of the patientsand in none of the asymptomatic participants (Fallerini et al.,2021).