The GATA1 protein (along with GATA2) is the master regulator of erythroid lineage maturation, including erythropoiesis, and a large-scale GWA study of the Malaria Genomic Epidemiology Network [13] reinforced the role of these ATP2B4 gene regions and their potential GATA1 regulation in malaria susceptibility. The gene discussed is ATP2B4; the disease is malaria.