We also observed a high frequency of ARGs conferring resistance to antibiotics that are used to treat infections not caused by E. coli but rather caused by Gram-positive bacteria, such as rifampicin (arr, n=394/110, respectively, 100 % identity and variants) and macrolide-lincosamide [lnu (n=494/322), mef (n=258/21), mphA (n=8661/408), erm (n=81/1405), vga (n=1/0) and msr (n=76/2)]. Here, ETV5 is linked to infection.