AQP2 and chronic kidney disease: It has been reported that the AUC values of more than 0.9 and 0.8–0.9 are considered to represent excellent and good biomarkers, respectively (El Khouli et al., 2009), and therefore release of uEV‐AQP1 and ‐AQP2, and two in combination, could be used as biomarkers to detect advanced CKD such as CKD G4 and G5.