Compared with the RV, the human LV had significantly higher expression of NLRP3 (2.3 vs. 1.4, p = 0.036), cleaved p17‐IL‐1β (2.2 vs. 1.0, p = 0.042), MCP1 (2.2 vs. 0.6, p = 0.011), and IL‐10 (1.6 vs. 0.7, p = 0.011) after 8 h CIS. Here, CCL2 is linked to in situ carcinoma.