TOLLIP and idiopathic pulmonary fibrosis: Intriguingly, N-acetylcysteine therapy is reported to be efficacious for individuals with IPF with an rs3750920 (TOLLIP) TT genotype (Oldham et al., 2015), therefore elucidating underlying biology of interaction between DAMPs and their receptors along with future clinical trials targeting these entities might lead to substantial clinical benefit.