Interestingly some ACE2 variants were shown to be significantly associated with the onset of diseases such arterial hypertension, diabetes mellitus, cerebral stroke, coronary artery disease, heart septal wall thickness and ventricular hypertrophy all considered as comorbidity factors of COVID-19 (Kowalczuk et al., 2008; Lu et al., 2012; Pinheiro et al., 2019; Calcagnile et al., 2020). Here, ACE2 is linked to COVID-19.