SLC7A11 and neoplasm: Next, we validated the impact of circFNDC3B on OSCC cell growth in vivo. Tumorigenicity assays in nude mice showed that the silencing of circFNDC3B repressed the tumor size, tumor volume, and weight in the model (Figures 7A–C), suggesting that circFNDC3B contributes to OSCC cells growth in vivo. Besides, the miR-520d-5p expression was increased and SLC7A11 expression was decreased in the tumor tissues of circFNDC3B depletion group compared with the control group (Figures 7D, E).