TGFB1 and cancer: The following components principally play critical roles in tumorigenesis and metastasis, including dendrite cells (DCs), T lymphocyte, natural killer cells (NKs), tumor-associated macrophage cells (TAMs), cancer-associated fibroblast cells (CAFs), and myeloid-derived suppressor cells (MDSCs) as well as transform growth factor β (TGFβ).