TGFB1 and cirrhosis of liver: In addition to these aforementioned miRNAs and somewhat elusive information, 11 out of 13 miRNAs were shown to be involved in liver cirrhosis for the first time with bioinformatics analysis, and the expression of 7 miRNAs was proved to undergo significant changes in LX2 cells challenged with TGF-β1 in vitro.