Other researchers have successively confirmed the protective effect of L-NAT on PD (Thornton et al., 2014), Alzheimer’s disease (Fernandes et al., 2018), traumatic brain injury (Jha, Kochanek & Simard, 2019; Donkin et al., 2009), stroke (Turner & Vink, 2012), opioid withdrawal (Tumati et al., 2012) and OTA-induced HEK-293 cells (Agarwal et al., 2020) damage. The gene discussed is BRD2; the disease is stroke disorder.