Nevertheless, the expression level of FGFR2, which is also a target gene for miRNA-21-5p, is increased in HCC samples (n = 54) [20] Surely, the role of miRNA is multivariate and it may induce gene expression in some cases, but for today these cases are insufficiently studied [21]. This evidence concerns the gene FGFR2 and hepatocellular carcinoma.