The area under the curve (AUC) values of the tumor and NTL groups in the TRIM58 analyses were significant for all 3 lung cancer datasets and were as follows: AUCGSE63384=0.950 [P <0.001; 95% confidence interval (CI), 0.903–0.998]; AUCGSE62948=0.964 (P <0.001; 95% CI, 0.913–1.015) and AUCGSE32861=0.945 (P<0.001; 95% CI, 0.900–0.989) (Fig. 1C). Here, TRIM58 is linked to lung cancer.