IL6R and major depressive disorder: These risk factors include soluble interleukin-6 receptor level (Rosa et al., 2019; Raita et al., 2021), childhood BMI (Au Yeung et al., 2021a), adult BMI (Granell et al., 2014; Skaaby et al., 2018; Xu et al., 2019; Sun et al., 2020; Au Yeung et al., 2021a), major depressive disorder (Mulugeta et al., 2020), early pubertal maturation (Chen et al., 2020), age at puberty (Minelli et al., 2018), estimated glomerular filtration rate (Park et al., 2021), lifetime smoking (Shen et al., 2020), and linoleic acid (Zhao and Schooling, 2019).