TYMS and familial pancreatic carcinoma: In a study of pancreatic cancer, the expression of thymidylate synthetase (TYMS) in pancreatic cancer tissue and normal tissue is compared based on TCGA database, with its diagnostic value being explored through receiver operating characteristic (ROC) curve analysis, and Cox analysis revealed that the high expression of TYMS is related to poor OS and recurrence-free survival (RFS) (Fu et al., 2019).