Interestingly, the ferroptosis suppressor gene, ACSL3, was negatively related to three drug sensitivity, among which AP-26113 is a potent and selective ALK and ROS1 inhibitor for lymphoma, everolimus is an mechanistic target of rapamycin (mTOR) kinase inhibitor for renal cell cancer and some other tumors, and nelfinavir is a protease inhibitor for HIV infection. This evidence concerns the gene ROS1 and HIV infectious disease.