ERVW-1 and Autoimmunity: With ERVW-1 encoding a functional ancestral viral envelope glycoprotein and aberrant expression of this glycoprotein, Syncytin-1, associated with a number of malignancies and autoimmune conditions (Strick et al., 2007; Larsen et al., 2009; Sun et al., 2010; Mameli et al., 2012; Strissel et al., 2012; Mameli et al., 2013; Li et al., 2019a), we chose to examine it more closely in EBV+ BL cell lines HH514-16 and Akata, as well as in an EBV-derived B lymphoblastoid cell line (LCL).