In mice with hypoxia-induced pulmonary artery hypertension, FOXM1 mRNA and protein levels are increased in the lungs; moreover, constitutive SMC-specific knockdown of FOXM1 inhibits hypoxia-induced pulmonary hypertension and prevents the proliferation of PASMCs, although it does not inhibit PASMC migration (Dai et al., 2018). This evidence concerns the gene FOXM1 and pulmonary arterial hypertension.