FUS and amyotrophic lateral sclerosis: ALS-related FUS mutations leads to disturbances in several FUS functions such as RNA metabolism (Lagier-Tourenne et al., 2013; Zhang et al., 2013), DNA repair (Deng et al., 2014; Naumann et al., 2018; Wang et al., 2019), or response to stress (Dormann et al., 2010; Lenzi et al., 2015).