CD274 and neoplasm: We then rechallenged surviving mice (5/12 bintrafusp alfa-treated and 1/10 anti-PD-L1-treated) with A223 tumor cells s.c. 124 days after initial tumor cell transplant, and none of them had detectable tumor growth within 100 days while all naïve mouse recipients rapidly developed tumors within 30 days (Fig. 3g), indicating that surviving mice maintain a durable memory T cell response against A223 cells.