For the KEGG enrichment analysis (Fig. 7B shows the first 10 entries), we were not surprised to find in the two enrichment results that 5 of the first 20 entries overlapped, including PI3K-Akt signaling pathway, fluid shear stress and atherosclerosis, human cytomegalovirus infection, MAPK signaling pathway, and Cytokine-cytokine receptor interaction, these signaling pathways are directly or indirectly related to thrombosis. The gene discussed is PIK3CA; the disease is atherosclerosis.