TRBV5-1 and type 1 diabetes mellitus: Such close homology between two TCRs restricted to the same antigen in two individuals, along with the biased usage of the TRAV26-1 and TRBV5-1 genes separately or paired in three different T1D patients, is indicative of a public response elicited to the spliced HIP peptide when bound to HLA-DQ828.