Geneset enrichment analyses revealed higher immune geneset expression in baseline and on-treatment tumor biopsies from the partial response patient (Fig. 3b), specifically the allograft rejection, TNF-α, inflammatory response, IL-6/JAK/STAT3 signaling, and interferon gamma (IFN-γ) response pathways of the cancer hallmark genesets39. This evidence concerns the gene IL6 and cancer.