Therefore, one might speculate that infection with S. suis cps2 might induce capsule-specific IgM antibodies cross-reacting with the capsule of cps14. However, such cross-reaction has not been shown for porcine sera and serum raised in rabbits against cps2 as use for agglutination generally does not cross-react with cps14 suggesting important conformational differences [57]. The gene discussed is CD40LG; the disease is infection.