The percentages of viable milk macrophages (Annexin V−/PI−; Healthy quarters: 41.73 ± 3.30, C. bovis-infected quarters: 40.29 ± 4.33, P = 0.79) and apoptotic milk macrophages (Annexin V+/PI−; Healthy quarters: 39.20 ± 3.58, C. bovis-infected quarters = 31.86 ± 4.59, P = 0.17) did not differ by infection status. This evidence concerns the gene ANXA5 and infection.