Markers of lipogenesis and triglyceride synthesis like fatty acid synthase (Fasn), diacylglycerol O-acyltransferase 1 (Dgat1), Dgat2, Acetyl-CoA carboxylase (ACC1), and fatty acid binding protein 4 (FABP4) were lowered by the HF diet. The gene discussed is DGAT1; the disease is hydrops fetalis.