GPT and hepatotoxicity: In the baseline-hepatotoxicity group, ALT decreased from a mean of 129 IU/L (range: 73, 202) at baseline to 106.5 IU/L (range: 25, 356) by day + 7 (P-value: 0.58), 48 IU/L (range: 20, 80) by day + 14 (P-value: 0.02), 23.5 IU/L (range: 20, 27) by day + 28 (P-value: 0.03), 16.5 IU/L (range: 16, 17) by day + 42 (P-value: 0.009) and 17 IU/L (range: 17, 17) by day + 84 (P-value: not available, only one patient; Fig. 2a).