Glioblastoma (T05, T08, and T12) developed mutation as follows:USP22,TTN,SMC3,RFX4,RFX7,PREPL,PAN3,FAM58A,DSC1,DMD,COL4A5,NOXA1,HIP1R,FOLH1,DUOX2,CUL7,YBX2,TP53,SIK1,PIK3CA,KHSRP,CYP2A6, andATG16L2. The gene discussed is PREPL; the disease is glioblastoma.