Tumour spheroid size at day 6 for both static 3D and the microfluidic setup was expressed as fold increase in size over day 1 values and showed that a SW620 spheroid size reduction was indicative of potentiation activity of ATM inhibitor (AZD0156) over SN38 alone, only in the microfluidic Ibidi chip but not in static experimental conditions (Fig. 2c). Here, ATM is linked to neoplasm.