demonstrated that antigen-expressing MYC;Trp53−/− HCC evaded the immune system by decreasing CCL5 expression through activation of the β-catenin signaling pathway, and that CCL5 overexpression restored immunosurveillance in antigen-expressing MYC;CTNNB1ΔN90 HCC17. This evidence concerns the gene MYC and hepatocellular carcinoma.